Chapter VIII

SURVEY OF THE FACTS BEARING ON ACQUIRED IMMUNITY AGAINST
MICRO-ORGANISMS 207
The discovery of attenuated viruses and its application to
vaccination against infective diseases.—Vaccination by microbial
products.—Vaccination with serums.—The acquired immunity of the
frog against pyocyanic disease.—The acquired immunity against
vibrios.—Extracellular destruction of the cholera vibrio.—Part
played by two substances in Pfeiffer’s phenomenon.—Specificity
of fixatives.—Phagolysis and its relation to the extracellular
destruction of vibrios.—Part played by phagocytosis in the
acquired immunity against vibrios.—Fate of the spirilla of
recurrent fever in the organism of immunised
guinea-pigs.—Acquired immunity against the bacteria of typhoid
fever and pyocyanic disease.—Acquired immunity against swine
erysipelas and anthrax.—Acquired immunity against the
streptococcus.—The acquired immunity of rats against
_Trypanosoma_.