Chapter VII: Part 7

1. Dizziness when stooping, vertigo, the head inclines backwards. Aching in occiput and temples. Beating headache at vertex. 5. Slight pain at the pit of the stomach. This pain is followed by a very marked pricking sensation. These pains cease after eating. Little appetite. 10. Contraction of the eyelids. Twinkling of the eyes. Pale face. Haggard looks. Languid eyes, heaviness of the head. Loss of appetite. 15. Very hungry. Bitter mouth. Tongue coated white. Urine thick and reddish. Very drowsy, even in the day-time. 20. Weary pain in the bend of the right elbow. Vivid, sometimes extatic dreams. Chill and heat all over. Shuddering. Pain in the joints.

PETIVERIA TETRANDRA. (GOM.)

PET. MAPPA GRAVEOLENS (WELL.) PIPI. ERVA DE PIPI.

This bush is common in the fields around Rio-Janeiro, where it blossoms the whole year. Its branches are erect, somewhat sarmentose, slightly pubescent at their extremities, with alternate, glabrous, somewhat undulate leaves. Flowers small, scattered over long axillary or terminal spikes; perianth persistent, herbaceous, with four linear divisions. Stamens four, alternate with the divisions of the perianth and a little taller. A single ovary, surmounted by a style, divided into ten reflexed stigmata. Capsule flattened, containing a single seed. The roots are branching and very fibrous; they smell strongly of garlic.

We employ the recent root.

Prover: _Dr. Manuel Duarte Moreira._

1. Merry, disposed to sing. Deep sleep, longer than usual, for the first three days. Drowsy all day, with frequent yawning, but no desire to lie down. Insignificant or unpleasant dreams, scarcely recollected on waking. 5. Sleeps longer, the first day. Headache, on waking. Sleepy with yawning, after breakfast, the first day. Drowsy after dinner, but no sleep, second day. Shuddering all over, sweat; the hair stands on end, second day, 9 in the morning. 10. Heaviness of the head on waking, eight hours after taking the drug. Weight at the vertex, which seems to press on the brain, with heaviness of the eyelids and difficulty of opening them, without sleep. Deep-seated and dull pain in the upper part of the brain, worse when touched, talking or sitting; less when walking or moving about, first day. Same symptom on the second day, but less. Sense of fullness in the head, second day. 15. Sense of fullness in the head, as if it would split, especially after twelve o’clock, on the third day. Sensation as if hot water were thrown on the hairy scalp, penetrating to the brain, second day. The headache disappears on the third day, it becomes lighter and changes. Sight feebler and dimmer than usual. Painful heat at the margin of the eyelids, worse when closing the eyes. 20. Dim sight after dinner, second day. Fetid breath. Sensation in the throat as if one had swallowed some astringent substance. Sensation in the mouth and throat as if one had eaten some acrid and resinous fruit, second day, in the morning. Dull pain in the bowels and hypogastrium, second day. 25. Constipation for three days. Copious urination, in the morning. Light-colored, watery urine, without smell or sediment, third day. Violent lancinations cinder the right breast, at each inspiration. Slight pain at the sternum, when stooping. 30. The voice becomes hoarse from much coughing. Weariness and numbness of the left arm, with pain in the humero-cubital articulation, first day. Numbness of the tips of the fingers, especially the ring-finger. Sensation at the middle of the right thigh as if bitten by an ant; itching and heat after scratching. Cramp in the calves during the night, second day.

Second prover: _Mlle. Norma_, 21 years old, sanguine temperament, good constitution, pale face, melancholy disposition, chestnut-colored hair.

35. Disposed to laugh and jest, first day. Sad, desires to weep; shortly after, involuntary weeping, sixth day, morning. Long, deep sleep, the first three days. Sleeps all day, with frequent gaping, but no desire to lie down. Dreams about quarrelling, she does not recollect her dreams on waking. 40. First day, sleeps longer than usual in the morning. Headache on waking. Somnolence after breakfast, with gaping, first day. Drowsy after dinner, second day. Sad dreams about sick persons in her family, fifth day. 45. Profuse, cold sweat, and chilliness all over, with shuddering after the first sleep, sixth day. Shuddering throughout her body, when lying down. Febrile heat, pale face, cold hands, on the evening of the sixth day. Two small dark-yellow spots on the neck. Headache, with a small and feeble pulse; heat in the face, especially on the right cheek, which is felt very intensely, though the skin feels cool, first day. 50. Painful stitch in the forehead, worse when opening the eyes, with external heat of the head on the first day, at 2 in the afternoon. Stabbing sensation in the right temple, first day, at 3 in the afternoon. Dull pain, with beating in the left temple, third day. Aching pain in the temples. Pain in the forehead, with compressive sensation in the brain, aggravated by walking. 55. Eyes half closed, swollen externally, surrounded by blue margins, especially near the nose, for three days. Weight on the eyelids constraining her to close her eyes; in this state she sees a variety of figures, sixth day. The veins of the nose are swollen and bluish. Redness and heat of the left ear, for some minutes, third day. Stomach-ache with sensation of coldness internally. 60. Acute and seated pain in the whole stomach, when rising from a chair, suffocation, with cold feet, which obliges her to remain in bed, on the evening of the sixth day. Pains in the muscles of the superior and inner side of the elbow, like stings of ants. Contusive pain in the arms and legs. Heaviness and weariness of the limbs, sixth day, morning. 65. Numbness of the lower limbs, with aversion to exercise. Contusive pain in the arms and legs, sixth day. Cold feet, in bed, morning.

Third prover: _Mlle. Silvia_, 20 years old, sanguine temperament, good constitution, gay disposition.

Disposed to sing. Regular and deep sleep, longer than usual, the first three days. 70. Sleeps all day, with frequent yawning, but no desire to lie down. Unpleasant dream which she does not recollect on waking. Wakes at 4 in the morning, falls asleep again a quarter of an hour afterwards. Light and disturbed sleep, after breakfast, first day, 9 in the morning. Deep sleep at 10, same day. Deep sleep, second day. 75. General prostration, with disposition to lie down, but no sleep, third day, 9 in the morning. Sad dreams, which she does not recollect. No sleep in bed. Profuse and cold sweat, after her first sleep. Prickings at the right shoulder, followed by inflammatory redness for 15 minutes. 80. Lancinations or shootings through the whole body, as if needles were stuck in; followed by itching from the elbow to the hands, with small violet-colored spots on the arm, back and feet, second day. Pain at the outer part of the left arm, with a large, red, inflamed spot like erysipelas. Heat on the surface of the body as from exposure to the sun, the feet being cold. Pain at the vertex, as from a blow, dull pain on the top of the head, left side, worse when turning the head or walking, second day, 11 o’clock in the morning. Benumbing and deep-seated pain with pressure, in the temples, and dull pain on the vertex, second day. 85. At the moment if lying down in bed, explosion in the head, the noise passing through the ears, third day. Deep-seated pain, at times in the forehead, at times in the nape of the neck. Aversion to exercise, she wants to remain quiet. Laming numbness of the arm and legs, fifth day, morning. Heaviness in the forehead, when stooping, here and there, sixth day, noon. 90. Weight in the eyes, and prostration as from sleepiness, without however being sleepy. Sensitiveness to the light of day. Redness of the conjunctiva, especially near the internal angle of the left eye. Sudden inflammation of the left eye at dinner, continuing for three days. The flame of the candle looks yellow, and seems surrounded by a red halo. 95. Redness of the wing of the nose and left cheek, third day. Frequent sneezing after 12, fifth day. Redness on the left cheek. Sharp lancinations in the epigastrium from within outwards, fifth day, evening. Lancination in the stomach after dinner, seventh day. 100. Pain in the throat, with difficulty of swallowing saliva. Catarrh from the third to the fifth day. When lying down, sensation in the spine as if she had strained it by lifting a heavy weight, first and second day, evening; the pain is aggravated by raising herself again or by inclining backwards, and disappears when she inclines forwards. Numbness at the wrist, along the course of the cubital nerve, with sensitiveness to contact, second day, evening. Shooting throughout the body, followed by itching at the back part of the forearm, second day, morning. 105. Redness and intense inflammation at the outer part of the left forearm, second day, 11 in the morning. Burning pain at the left radius, with contusive sensation when touched, third day. Violent itching of the ball of the left thumb, followed by inflammatory swelling, third day, evening. Weariness of the arms and legs, and numbness as after a long walk, fourth day, morning. Painful numbness at the outer parts of the arms and legs. 110. Cold feeling in the interior of the bones, fourth day, noon. Numbness of the anus and legs, with deep-seated pain at times in the forehead, at others in the nape of the neck, with aversion to motion, fifth day, morning. Excessive coldness penetrating to the bones, hands and feet, seventh day. Sudden numbness of the knees, with dull pain in the tibia, first day, noon. Acute and lancinating pain in the metatarsal bone, which corresponds to the left little toe. 115. Painful pricking in the left fifth toe, eighth day, morning, a few moments after, the same toe feels as if it would turn round from above downwards.

Fourth prover: _Miss Célia_, 17 years old, sanguine temperament, good constitution, pale face, cheerful disposition, auburn hair.

Evanescent and confused ideas. Want of memory. Passing recollection, which escape from her mind without her thinking of it. Sadness unto tears, with headache, second day. 120. Deep sleep, commencing early, and lasting longer than usual, for three days. Drowsy all day, with frequent yawning, but no desire to lie down. Unpleasant dreams which she does not recollect on waking. Quiet sleep in spite of the disturbing dreams which she forgets on waking, second day. Prostration as from sleepiness, without desiring to sleep. 125. Dreams about dead bodies, she wakes with a start and cold sweat all over her body. Sensation as if the finger were pressed on the right temple, with sensitiveness to contact, second day, noon. Lancinating pain in the right temple, suddenly shifting to the left temple and thence to the vertex, where a burning sensation is experienced, second day. Pain and heat in the forehead, with pressure on the eyes, second day, three in the afternoon. Dull pain at the root of the nose, evening. 130. Numbness and compressive sensation as if a warm bandage were wrapped round the head. General prostration as from sleepiness. The voice seems to come from afar. The body seems insensible when she is lying down, and she feels as if in a swoon. When walking she feels as if she did not touch the soil, and as though she would fall. 135. Painfulness of the eyes, as if the eyeballs were driven out of the orbits by some foreign body. Sensation as if the head were full of warm water. Sadness, tears; in her sadness she remains seated, motionless, speechless (all these symptoms occurred within an hour, second day, after 12). Headache, with weight on the eyes, second day. Sensation as if stung by ants under the left lower eyelid. 140. Nose slightly inflamed and shining. Dull pain at the root of the nose, on the evening of the first day. Pain at the left wing of the nose, which spreads to the opposite side, followed by bloating on the dorsum of the nose, second day, at noon. Sense of heat in the face, though the skin feels cool. Sensation as if a needle had been stuck in the upper lip from within outwards, eleventh day, on rising in the morning. 145. Toothache. Dry mouth. Burning tongue as from hot water, on rising from bed. On going to bed, flow of watery and cold saliva, depositing an ash-colored sediment and whitish granulations, which taste and smell like bile, but are not bitter. Sharp and lancinating pain striking through the spleen from below upwards, second day. 150. Slight colic in the descending colon. From 11 in the morning until evening she urinates every five minutes, with heat in the urethra, second day. She urinates three or four times an hour, without pain, third day. Urine colorless, on the following days. Tightness and beating in the region of the heart, fourth day, evening. 155. Deep-seated and dull pains in the chest, under the sternum. Dull pain in the posterior cervical region, when moving, the neck, second day, noon. In the right wrist-joint she feels an internal, sharp pain which seems to be more violent externally. A similar pain is felt at the left wrist, but less intense. Pain from the humero-cubital articulation to the wrist. 160. Numbness at the posterior and internal part of the forearm. Sharp pain, and sensation of painful roughness at the forearm, first day, evening. Pain in the right hand, from the circumference to the centre. Sudden pain at the left little finger, striking through the whole forearm, becoming seated at the humero-cubital articulation and increasing gradually, with sensation of constriction, second day, morning. Shooting, and itching at the internal and upper part of the forearm, second day, morning. 165. Pains in the last fingers of the right hand as if they had been struck with a hammer, second day, noon. Sweat in the palm of the hands, second day, evening. Twisting sensation in the scapulo-humeral articulation, when stooping, third day. Sense of paralysis in the forearms and the phalangeal articulations, the fingers feeling numb, third day, evening. Heat in the skin of the arm, as if slightly burnt, after rubbing the hand over it. 170. Slight crampy pain in the tendons of the palms of the hands, and in the forepart of the wrist. Similar pain in the tendons of the ring-fingers, sixth day. Renewed crampy pain in the hands, ninth day. Cramp in the right ring-finger, tenth day. Slight cramps in the hands, twelfth day. 175. Numbness from the knee to the sole of the foot, where it becomes seated, first day, noon. Weakness and numbness of the legs, especially when rising, first day, after 12 in the day-time. Weakness in the legs and knees when stooping. Weakness in the legs, so that the knees give way, second day, after 12. Pain at the forepart of the tibia, as from a blow. 180. Contusive pain at the calf, aggravated by contact. Dullness of the sentient faculty when lying, as if the body were numb.

Fifth prover: _Miss Nina_, 14 years old, sanguine temperament, cheerful disposition, red face, auburn hair.

The least cause excites her mirth; she would like to sing. Regular sleep, generally longer than the three first days. Drowsy all day, with frequent yawning, without any desire to go to bed. Dreams which she is unable to recollect. Lachrymation, with sensation as of sand in the eyes. Urine more profuse and of a lighter color. Numbness of the right arm.

Sixth prover: _Mr. Cyprien Huet_, 51 years old, sanguine temperament, robust constitution, serious disposition, red conjunctiva, weak sight, redness of the margin of the eyelids.

Very gay. He laughs and sings all day. Deep sleep, commencing sooner and ending later than usual, for four days. Quarrelsome dreams, second day. Violet-colored spots elongated horizontally, on the right hypochondrium. Dull pain at a point on the hairy scalp, and pressure at the occiput on the right side. 195. Boring pain at the top of the forehead, second day. Contusive pain at the zygomata. Violent lancinations in the upper part of the forehead and in the left side of the head, for one minute, second day, noon. Pain in the upper part of the left parietal bone, as if the skull would split. Boring pains in the right upper lid, first day. 200. Dull pain at the right eye, as from a blow, relieved by pressure, second day, noon. Slight pain in the nose. Intense and sudden itching on the dorsum of the nose. Stoppage of the right ear, with hard hearing. Contusive pains in the outer parts of the orbits. 205. Sensation as of a pustule on the cheek, of the size of a pea, for some seconds. Violent itching at the same place. Sensation in the throat as from swallowing some astringent substance. Borborygmi when lying down, second day, morning. Lancination in the hypochondria. 210. Mucous diarrhœa, dark-colored, mixed with fæcal matter in hard and single fragments, third day. Light-colored and copious urine, second and third day. Dry heat in the palms of the hands, for several days. Sense of contusion in the muscles of the right forearm, at the inner side between the radius and cubitus, first day, morning. Crampy pain in the muscles of the right hand, especially at the thumb, first day, morning. 215. Dull pain and numbness, as is experienced when pressing the brachial nerve where it passes over the internal condyle of the humerus; aggravated by contact, first day, noon. Violent crampy pain in the muscles of the palm of the right hand, for five minutes. Crampy pain in the left little finger. Numbness of the fingers of the right hand for several hours, first day, after 12. Lancination and heat at the tip of the right thumb, as if there were a whitlow, extending to the first phalangeal articulation. 220. Heaviness and numbness of the extremities, first day, evening. Contusive pain at the forearm. Itching at the last fingers. Numbness of the extremities after rising from bed, second day, three different times. Itching in the palm of the left hand. 225. Pain in the external middle part of the right forearm, as if needles were thrust in. A similar feeling at the left arm, but less distinct. On rising from bed, in the morning, numbness and itching at the right foot, first day. Dull pain in the knee-joint and bend of the knee, especially the first day. Numbness and slight itching of the right leg, down to the foot, second day, noon. 230. Slight, acute and circumscribed pains in the groins, repeatedly and at intervals. Heat in the loins, second day. Dry heat all over, especially in the palms of the hands. General weakness, every morning after rising from bed.

ARRANGEMENT ACCORDING TO HAHNEMANN.

MENTAL, MORAL, HEAD: 1. Sad. Sad, motionless, speechless. Confused ideas. Merry, disposed to sing. 5. Boring pain at the top of the forehead. Lancinations in forehead and left side of the hand. Splitting pain in left parietal bone. Pain and head in forehead, with pressure on the eyes. Numbness and compressive sensation at the head as from a warm bandage. 10. Sensation as if the finger were pressed on the right temple. Lancing pain in the temples, shifting to the vertex where she feels a burning. Pain at vertex, as from a blow. Numb pain, with pressure, in the temples. Heaviness in the forehead when stooping. 15. Headache, with small pulse and hot face. Painful stitch in forehead, worse when opening the eyes. Stabbing sensation in right temple. Dull, beating pain in left temple. Compressive pain in forepart of head. 20. Headache on waking. Heaviness of the head, also at the vertex. Sense of fullness in the head, as if it would split. Sense as if hot water were thrown on the hairy scalp. Deep-seated pain in upper part of the brain, less when walking about. 25. Dull pain at a point on the hairy scalp.

EYES, &c.: Lachrymation and feeling as of sand in the eyes. Boring pains in right upper lid. Dull pain at the right eye as from a blow. Pain as if the eyes were driven out. 30. Stinging under the left lower lid. Redness of the conjunctiva. The flame of the candle looks yellow. Eyes half closed, bloated. Weight at the eyelids, she has to close them and then sees figures. 35. Dimness of sight. Painful burning at the margin of the eyelids. Toothache. Sense of heat in the face. Itching of the dorsum of the nose. 40. Nose inflamed, shining. Pain at the alæ nasi, followed by bloating of the dorsum of the nose. Stoppage of the right ear. Report in the ears when lying down. The left ear is hot and red.

MOUTH, STOMACH, &c.: 45. Stitching in the upper lip. Dry mouth. Burning in the tongue. Flow of saliva in the evening, with ash-colored sediment and granulations tasting like bile. Sore throat with difficulty of swallowing saliva. 50. Astringent sensation in the throat. Lancinations in the epigastrium and stomach. Stomach-ache, with cold feeling internally. Acute pain in stomach when rising from a chair. Circumscribed pains in the groins. 55. Rumbling. Lancing pain in the spleen. Dull pain in bowels.

STOOL: Constipation. Slimy diarrhœa. 60. She urinates every five minutes, with heat in the urethra. Light-colored urine.

BRONCHIAL: Cough with hoarseness. Suffocation, with cold feet, in bed. Fetid breath. 65. Pain at the sternum when stooping. Deep-seated pain under the sternum. Tightness and beating in the region of the heart.

EXTREMITIES: Heat in the loins. Twisting sensation at the shoulder-blade, when stooping. 70. Sensation in the spine as if strained when lying down. Prickings at right shoulder, followed by inflammatory redness. The left arm feels weary and numb. Pain at left arm, with large, red, inflamed spot. Burning pain at left radius. 75. Inflammatory redness at left forearm. Sense of paralysis at the forearm and phalanges. Shootings and itching at the inner forearm. Numbness at the inside of the forearm. Sharp pain and rough feeling at the forearm. 80. Pain in the forearm. Contusive sensation at right forearm. Pricking pain at the outer and middle part of the right forearm. Numbness of the right fingers. Stinging pains at the elbow. 85. Numbness at the wrist with sensitiveness to contact. Internal sharp pain in right wrist. Crampy pain in the palm of the hand. Sweaty in the palms of the hands. Pain in the fingers of the right hand, as from a blow. 90. Pain in the right hand. Dry heat in the palms of the hands. Crampy pain in the muscles of the right hand. Numbness of the tips of the fingers. Itching and inflammatory swelling of the ball of the left thumb. Cramp in the ring-finger. 95. Sudden pain from the little finger to the extent of the forearm, with constriction at the elbow. Darting and heat at the tip of the right thumb. Numbness of the lower limbs. Biting sensation at right thigh, with itching and smarting after scratching. Cramp in the calves, at night. 100. Numbness of the legs, also with weakness. Contusive pain at the calf. Numbness and itching of the right leg. Sudden numbness of the knees. Dull pain in the knee joint. 105. Lancing pain in the metatarsal bone. Painful pricking in the left fifth toe, followed by a sensation as if it would turn.

SLEEP: Drowsy, yawning. Deep sleep. Drowsy after breakfast and dinner. 110. Light sleep. Sad dreams about sick persons. Dreams about quarrelling. Unpleasant dreams. Sad dreams. 115. Dreams about dead bodies, she wakes with a start and covered with cold sweat. Quarrelsome dreams.

FEVER: Febrile heat, pale face, cold hands. Heat all over. Dry heat all over. 120. Shuddering all over. Cold feeling in the bones. Profuse cold sweat and chilliness, first part of the night.

CUTANEOUS: Violet-colored spots on the right hypochondrium. Two yellow spots on the neck.

GENERAL: 125. Heaviness and numbness of the extremities. Weakness every morning. The body feels insensible when lying down, as if in a swoon. Prostration. Dartings through the whole body, followed, by itching and violet-colored spots on the arm, back and feet. 130. Numbness of the arms and legs. Contusive pain in the arms and legs. Heaviness of the limbs.

JANIPHA MANIHOT. (KUNTH.)

JAN. JATROPHA MANIHOT. (LIN.) MANIHOT UTILISSIMA. (POHL.) MANIOCA MANDI.

The manioca which is cultivated, a good deal in South-America, for its nutritious root, is a bush with a round and ramose stem, often growing to the size of three feet high. Its leaves, which are of a sea-green color, and supported by long petioles, are alternate, palmate, with five to seven lanciolate, smooth and entire lobes. The flowers, which are monoïchous, form branching panicles either terminal or axillary; their perianth is calicoïd, campanulate, with five deep divisions of a light-yellow color, changing to a brown at the extremity of the divisions. Flowers male, ten stamens, with alternately long and short filaments inserted in a fleshy disk, which, in the female flowers, surrounds the base of a sub-globular ovary, with three uni-ovulate chambers; no style, but three stygmata presenting six or seven thick, compressed lobes that constitute a thick and sinuous mass. The roots, which are tuberculous and very big, contain an abundance of milky juice which is very poisonous when fresh, and which is extracted first by pressure and afterwards by the desiccation of the feculent portion that constitutes the chief nutriment of the Brazilian farmer. It is this juice that we employ in medicine.

On the second of July, 1845, a large quantity of this dangerous liquid was expressed before the institute, and an ounce of it was taken by Dr. Jo. Vincente Martins, and several pupils among whom Messrs. Antonio de Souza, Dias and Chedifer, seemed to be the most eager. The symptoms were so violent that most of the provers were obliged to antidote them. We trust that the devotedness of the Brazilian physicians will excite a corresponding enthusiasm among their brethren in other parts.

_First day._—1. Eructations, at half past 6 in the morning. Slight feeling of dryness in the œsophagus. Slight weight in the stomach. Drowsy in the day-time. 5. Thirst. Falls asleep late. Stool easier than common. Pain at the velum palati. Pain in the orbits. 10. Pain in the chest. Weakness of the knees in going up-stairs. Sad. Feeble. Dizzy. 15. Acute pain in the left arm, at night.

_Second day._—Vague pain in the abdomen, while urinating, at 6 in the morning. Copious light-colored, watery, fetid stools. Renewed ineffectual urging to stool, at 8. Appetite when commencing breakfast, it suddenly ceases after taking a little milk. 20. Sense of swelling in the left tonsil. Profuse sweat during sleep, ceasing on waking. Watery, greenish, fetid stools. Slight dull pains in the stomach and bowels, with rumbling. Sudden pain, with lancination in the urethra, above the fossa navicularis, for two minutes. 25. Tenesmus and pressure in the sphincter ani, with pricking, at 3 in the afternoon. Weight in the head, especially high up in the forehead, at 4 in the afternoon. Drowsy, at 4 in the afternoon. Distressing dreams, he wants to save a child from asphyxia, but the parents refuse to have it treated. Dizzy. 30. Wakes in bad humor. Trembling of the knees and limbs, with violent emotion when hearing other persons talk about the malady which he fears he is afflicted with. Pain in the side of the chest and in the shoulders, worse during motion.

_Third day._—Uncertain and transitory, but very acute pains in the stomach. Fetid sweat in the axillæ and about the scrotum. 35. Doughy mouth, with bad breath. Noise in the ears like that of rushing steam. Slight heat in the urethra. Swelling of the ankles, rather less at night. Pain in the back. 40. Pain at the left elbow. Moral and physical prostration.

_Fourth day._—Heaviness in the stomach, all night, eased by placing the hands upon the part. Optical illusions. Bitter mouth. 45. Pain in the forehead and the nasal fossæ.

_Fifth day._—Pain at the inside of the thigh. Dreams about a fire with little flames like those which were observed during the examination at the institute of Rio Janeiro from the tenth attenuation of the crotalus cascavella, by means of the solar microscope.

_Sixth day._—Drowsy. Diarrhœa in the morning. 50. Pain at the loins. Icy coldness of the knees.

_Seventh day._—Icy coldness under the shoulder-blades, in bed, even when well covered. Cold feet and hands.

_Eighth day._—Rheumatic pain in the right thigh. 55. Icy coldness in the arm, even to the marrow. The whole head, especially the nape of the neck, is cold.

ARRANGEMENT ACCORDING TO HAHNEMANN.

Dizzy. Sad. Bad humor on waking. The whole head and especially the nape of the neck, are cold. Weight in the head. Pain in forehead and nasal fossa. Optical illusion. Pain in the orbits. Whizzing in the ears. Eructations. Thirst. Appetite at breakfast, ceasing suddenly after tasting milk. Doughy mouth. Dry feeling in the œsophagus. Pain at velum palati. Sense of swelling in left tonsil. Dull pain in stomach and bowels. Weight at the stomach. Tenesmus, and pressure in sphincter ani, with pricking. Watery, fetid stool. Ineffectual urging to stool. Painful darting in the urethra. Heat in the urethra. Vague pain in the abdomen when urinating. Pain in the side of the chest, during motion. Pain in the chest. Fetid sweat in the axillæ. Acute pain in the left arm. Pain at the left elbow. Icy coldness in the arm. Cold feet and hands. Rheumatic pain in the right thigh. Trembling of the knees and limbs. Swelling about the ankles. Weakness of the knees: Icy coldness under the shoulder-blades, in bed. Distressing dreams. Drowsy. Dream about little flames. Sweat during sleep. Prostration.

MELASTOMA ACKERMANI.

MELAST. TAPIXIRICA.

This species has never yet been described by authors. It is a bush with round branches, triangular at their extremities, and covered with a brownish bark. The leaves are opposite, supported by short and hairy petioles; their limb is oval, reticulate, covered with stiff hairs, and traversed on its lower surface by five thick almost parallel nerves running from the base to the summit of the leaf. The flowers are sessile supported by terminal axes. We employ the leaves.

_First day._—1. In the morning, pain in the region of the sternum. Sneezing. Heat all over. Palpitation of the heart. 5. Buzzing in the left ear. Acid stomach. Profuse saliva. Shuddering, then sweat. Vertigo.

_Second day._—10. Looseness of the teeth. Lancination and prickings at the vertex. Stitches at the feet, ankles and wrists. (Disappearance of an inveterate diarrhœa with colic). Itching and heat at night. Tenesmus with constriction of the sphincter. 15. Pain at the perinæum. Light-colored and foaming urine. Hardness of the penis, even when there is no erection. Fetid urine. Digging in the teeth. 20. Heat and pricking at the anus. Pricking in the urethra. Weakness of the thighs. Profuse urine. Lancinations in the perinæum, the urethra and the testicles. 25. Rumbling. Urine more cloudy and less foaming. Pain in the abdomen. Prostration. Pale face. 30. Drowsy in the day-time. Urine with white sediment. Albuminous urine. Horrid pain and pulling from the perinæum to the groin, for six hours; while seated and not passing off in any position. Violent shuddering for four hours, followed by heat without sweat. 35. White coated tongue. Bitter mouth. Pain in the loins. Red urine without smell, with bloody coagula. Headache and sensitiveness of the hairy scalp. 40. Œdema of the legs. Eruption on the lips, especially the upper. Internal heat.

SEDINHA.

Herbaceous plant, with a slender, round and pubescent stem; the leaves are opposite, lanceolate and very sharp; their upper surface is hairy and of a darker green than their lower surface, which is covered with long, silky hairs. This plant is quite common in the neighborhood of Rio-Janeiro. We employ the leaves.

1. Aching pain at the sternal articulation of the fourth ribs. Internal itching, with desire to scratch, in the pit of the stomach. Sensation in the region of the liver as if penknives were thrust in. Tenesmus. 5. The urine burns like boiling water. Restless dreams about murders, monstrous animals. Distress on seeing any one eat. Pain in the pit of the stomach in raising one’s-self. Pressure in the temples and vertex. 10. Bone-pains above the eyes. Constant yawning for two days. Pain in the abdomen, after dinner, apparently proceeding from the pit of the stomach, with slight colic. The teeth are sensitive and set on edge, especially the right upper incisores. Itching in the left ear, with a good deal of ear-wax. 15. Digging pain in the right lung. He raises a bloody mucus. Desquamation on the back of the hand, extending to the nails, where the skin becomes loose and forms hang-nails. Itching at the pubis. Pimples and itching on the back, chest and arms. 20. Colic in the evening, with incarcerated flatulence; relief is obtained by the emission of flatulence. Toothache after eating, with bleeding and sensitiveness of the gums. Pain in the bad teeth. Headache as if from water-bubbles enclosed here and there in the forehead. Sense of excoriation in the urethra. 25. Slight pain in urinating. Discharge from the urethra of a water mixed with little mucous flocks. Heat on the back of the hand as if scorched by the sun, followed by desquamation. The gums are extremely sensitive, and the incisor teeth set on edge. Ludicrous dreams; he is pursued by crocodiles and he drives them away by sneezing. 30. Coffee aggravates the symptoms; the incisor teeth are set on edge, with sense of coldness in these teeth which descends from time to time. Caries of an incisor tooth.

SPIGGURUS MARTINI. (NOBIS.)

SPIG. SPIGGURUS SPINOSA (FR. CUV.) HISTRIX SUBSPINOSUS. THE PORCUPINE.

This little animal is common in Brazil where it lives on trees and secures itself by means of its hind-feet, it uses its tail, which is pretty long, as a means of descending. Its length, from the muzzle to the tip of the tail, is about a foot; the tail is almost as long as the trunk. The upper parts of the body are covered with sharp prickles about an inch and a half long, and attached to the skin by means of a very thin pedicle. The head-prickles are white at the base, black in the middle and of a yellowish-brown at the top, the dorsal prickles are of a sulphur-yellow at their base. The prickles on the rump and the first third of the tail, are black at their extremity. All the prickles are very close together, mingled with a few long and fine hairs. The lower limbs are covered with a grayish fur, interspersed with little prickles; the tail is furnished with prickles at its upper part, and is covered with stiff and black hairs; the extremity of the tail is bare.

We triturate the prickles taken from one of the sides.

Prover: _Jo. Vincente Martins._

_First day._—Took one dose of the third trituration at 8 in the morning. 1. Desire to vomit and nausea at the sight of food, immediately. At night, sense of dryness and fullness in the stomach. Very drowsy after dinner.

_Second day._—5. Wakes early. Merry and quiet dreams. Sense of fullness in the abdomen, at 5 in the morning, when lying. Diarrhœa. Transitory pains in the toes, right temple and one of the right cuspidati. 10. Pains at the lower extremity of the right forearm. Pain at the right zygoma. Pain at the first incisor. Bleeding of the gums. Pain in one half of the head. 15. Buzzing in the ears. The knees give way, likewise the tarsal joints. The toothache becomes obstinate. After dinner all the pains cease. Shuddering with chattering of the teeth. 20. Cough with pains in the chest. Stitch in the region of the heart, left side, which stops his speech for two minutes. Pain at the right arm, from the hand to the elbow, as if extending the arm were prevented by a string. Improvement when turning the arm or lifting a weight, or moving it about; aggravation as soon as these movements cease. After breakfast, boring pain through the bones of the skull. 25. Aggravation when lying down, and improvement when walking in the open air. Pains in the stomach, as if strung together.

_Third day._—Quiet sleep with merry dreams; in the morning he dreams of insects and a serpent which it was difficult to kill. Painful sensation at the articulation of the jaw. Whizzing and buzzing from the left ear to the back part of the head. 30. Long-lasting prickings at the zygoma. Very much disposed to write, in the morning, ceasing after breakfast. Heaviness of the head from 10 to 11. Abundant desquamation in the region of the whiskers and at the knee. The whizzing in the ears continues. 35. Acute pain in the intercostal muscles, in the evening, while riding on horseback. Prickings on the vertex from time to time, especially on the right side. Pain at the lower extremity of the forearm. Dizziness in the back part of the head when writing. Roaring in the ears, as from a distant gale. 40. Bitter mouth and throat, with salt taste. Nausea, with piercing pain in the back, for 15 minutes.

_Fourth day._—Boring pain through the skull-bones. Cough as the day before. General weakness. 45. Drowsy all day. Lancination in the left side of the head, through the skull-bones; inability to move the head, for three minutes. When sitting or rising, lancinating pain in the right big toe hindering walking, for two minutes. 50. Painful swelling of the abdomen, before dinner. Itching of the pubis after taking tea.

_Fifth day._—Disposed to yawn, with flow of saliva. Lachrymation. Stitch in the left side, for five minutes, hindering gaping. 55. Shootings in the epigastrium, for several minutes. Pain in the left side, at the moment when he attempted to gape. Acute pain from the left ear to the jaw, for two minutes. Constriction from the neck to the diaphragm, with heaviness of the head and arms. 60. Numbness for half an hour. Pain in the right side, for two minutes, as if a plug were thrust in. Pain in the urethra after urinating, worse when stooping in order to pick up something. Pain around the navel. Continued swelling and pain of the abdomen, down to the left groin. 65. Drowsy. Good appetite. Nausea after dinner. Shuddering from time to time. Heat and numbness of the feet. 70. Merry dreams, at night.

_Sixth day._—Itching all over, with bleeding after scratching. Pain in the right arm, as if the bones were broken, with inability to grasp any thing. Deafness on the left ear, as if stopped. Inconsistent and capricious mood.

_Tenth day._—The scales on the head and in the whiskers are less; before, they were so thick that he did not feel either the cold or heat, and was insensible to water. Irritable, he quarrels about the least trifle. Cracks between the toes. Violent pain in the left kidney. Constant whizzing in the ears. 80. The speech is sometimes embarrassed. He discovers some gray hairs. His hair falls off. Every thing is disagreeable to him; he desires to travel.

ARRANGEMENT ACCORDING TO HAHNEMANN.

Dizziness behind the head. Capricious mood. Every thing is disagreeable to him, he desires to travel. Prickings on the vertex. Darting through the left skull-bones. Hemicrania. Boring pain in the skull, after breakfast. Heaviness of the head. The hair falls off. Lachrymation. Deafness on the left ear. Whizzing in the ears. Buzzing in the ears. Pain in the articulation of the jaw. Bleeding of the gums. Pain at the right zygoma. Prickings at the zygoma. Bitter mouth, with salt taste. Nausea, with piercing pain in the back. Desire to vomit at the sight of food. Drowsy after dinner. Embarrassed speech. Constrictive pain in the stomach. Dry and full feeling at stomach, at night. Painful swelling of the abdomen, before dinner. Shootings in the epigastrium. Pain in right side as from a plug. Pain around the navel. Violent pain in the left kidney. Sense of fullness in the abdomen. Pain in the urethra, after urinating, worse when stooping. Itching of the pubis, after taking tea. Cough with pain in the chest. Stitch at the heart. Constriction from the neck to the diaphragm. Pain in the intercostal muscles. Pain in right arm, as if broken. Pains at lower end of the right forearm. Pain at the right arm, as if the stretching were prevented by a string. The knees give way. Heat and numbness of the feet. Cracks between the toes. Lancing pain in the right big toe. Yawning. Morning-dream about a serpent. Merry dreams. Shuddering. Shuddering, with chattering of the teeth. Desquamation at the whiskers. Itching all over, with bleeding after scratching. Pains in the toes, right temple. Feels better in the open air.

CONVOLVULUS DUARTINUS. (NOBIS.)

CONVUL. DUART. CALONYCTION SPECIOSUM. (D. C.) IPOMEA BONA NOX. (LINN.) CONVOLVULUS PULCHERRIMUS. (WELL.) MORNING-GLORY.

This is a climbing plant, cultivated in America and Europe. Leaves large, entire, cordate, alternate, on long petioles, generally arising from the axil of the flower-bearing branches. Calix with five unequal folioles, the three outer ones sharp, the two inner ones oval and foliaceous. Corol white, large expanding into a large circular limb. Stamens five, adhering by their filaments to the tube of the corol which is shorter than the stamens. Anthers linear acuminate. The base of the ovary is surrounded by a glandular disk; style very long, filiform, terminated by a shaggy, bilobate stygma; fruit with a coriaceous tegument. There are two or three flowers on the flower-bearing pedicels; they resemble a trumpet in shape, whence their Brazilian name “herva trombetta.” This plant blossoms in the summer-months. We employ the flower.

Prover: _Dr. Manoel Duarte Moreira._

1. Heat and burning of the skin all over, with prickings like the stings of insects. Profuse sweat in bed, several nights in succession. Red spot on the right cheek when rising from bed, it disappears in the course of the day. Shuddering in the day-time, several different times. 5. Small red spot in the right side of the neck. Drowsiness in the evening, in three provers. Prostration, in two provers. Dreams about quarrels. 10. Reveries in the day-time. Dreams about dead persons and about the incisores falling out. Dreams that one flies along an illuminated street; appearance of a ghost; waking with a start. Languor. Sinking of the moral strength, in two provers. 15. Hypochondria. Mental languor. Discouragement. Pain in the left temporal region, in relation with the eye. Pain at the right cheek. 20. Pain in the frontal region. Dizziness, in three provers. Pain all over the head, especially along the median line. Pain in the frontal region, with heat at the root of the nose, in three provers. Two small spots on the forehead, disappearing in a few minutes. 25. Pain in the whole head, from the morning until 5 o’clock in the evening. Acute pain in the left temporal region, in the morning, on two consecutive days, in two provers. Headache, at times at the vertex, at others at the occiput. Pain in the temples. Violent pain at the vertex, evening. 30. Pressure in the frontal region. Headache on the left side. Heaviness and dizziness in the frontal region, two days in succession. Burning in the frontal region, ceasing after taking a cold bath. Violent pain at the vertex, morning. 35. Vertigo with fainting. Slight pain at the vertex. Inflammation of the left eye. Dark redness of the face. Slight heat in the upper part of the œsophagus. 40. Sore throat for eight days. Sense of swelling at the tongue. Toothache. Swelling of the gums. Bad taste in the mouth. 45. Spitting up of mucus. Heat and dryness at the anterior and superior part of the œsophagus, in three provers. Slight pain on each side of the thyroid cartilage. Appetite when rising in the morning, in two provers. Stomach-ache for three days. 50. Decrease of the appetite. Pain in the abdomen, with internal heat. Violent colic with pulling, in two provers. Constipation, the first days, in eight provers. Red urine. 55. Yellow sediment in the urine. Numbness of the left scapular region. Pain at the left shoulder. Numbness of the arm, worse when hanging down. Numbness of both arms. 60. Deep-seated pain in the left forearm. Numbness of the right index- and middle-finger. Pain in the left wrist-joint. Deep-seated pain under the right breast. Pain at the right knee. 65. Deep-seated pain in the calves. Pain at the forepart of the left leg, for four days. Laming pain of the legs and thighs for several days. Deep-seated pain, first in the left, then in the right thigh. Numbness of the left leg and heel. 70. Shooting stitch in the right knee.

ARRANGEMENT ACCORDING TO HAHNEMANN.

MENTAL, MORAL, HEAD: 1. Vertigo with fainting. Dizziness. Pain all over the head. Headache, at the vertex and at times at the occiput. 5. Pressure in the frontal region. Burning in the frontal region. Pain in the left temporal region, also acute. Pain in the frontal region, also with heat, at the root of the nose.

EYES, &c.: Inflammation of the left eye. 10. Swelling of the gums.

MOUTH, STOMACH, &c.: Sense of swelling at the tongue. Sore throat. Heat in upper part of the œsophagus. Bad taste in the mouth. 15. Decrease of appetite. Stomach-ache for some days. Pain in abdomen, with internal heat. Colic, with pulling. Constipation. 20. Red urine. Yellow sediment in the urine. Deep-seated pain under the right breast. Pain on each side of the thyroid cartilage. Numbness of the left scapular region.

EXTREMITIES: 25. Pain at left shoulder. Deep-seated pain in left forearm. Numbness of the index- and middle-finger. Numbness of the arms. Deep-seated pain in the calves. 30. Laming pain of the legs and thighs. Deep-seated pain in the thighs. Numbness of the left leg and heel. Shooting stitch in the right knee.

SLEEP: Quarrelsome dreams. 35. Reveries. Dreams about dead persons and about teeth falling out. He dreams that he is flying along an illuminated street. Burning of the skin all over, with stinging. Profuse sweat in bed. 40. Shuddering, repeatedly. Red spot on the right cheek, when rising from bed, also on the neck. Prostration, also moral.

BUFO SAHYTIENSIS. (NOBIS.)

BUFO. BUFO AGUA (LAT.) TOAD.

This toad is found all over America; it inhabits swamps and marshy regions. It is as big as two fists, though its size varies a good deal. It is readily known by its enormous rhomboïdal parotids, whence it sends forth a large quantity of poison. Its head is flat, triangular, more large than long; it shows a strong osseous edge, commencing at the tip of the muzzle, thence stretching towards the inner angle of the eye, round this organ, and finally terminating behind the lids. The eye and the tympanic wall are very large. The trunk, which is very large anteriorly, in consequence of the large development of the parotides, is covered, on each side of the dorsal spine, with two irregular rows of large elliptical or conical bladders; sometimes there are such bladders on the sides. The anterior extremities do not reach to the end of the trunk; the posterior extremities reach beyond the muzzle by the length of the fourth toe. The toes are rather flattened; the first toe is longer than the second. Its colors are various, consisting of a number of brown spots, which coalesce on the back, and are separated on the abdomen by yellowish dots.

The horrible croaking of these animals is well known, and might rouse the indignation of the most phlegmatic individual.

By exciting the animal, we caused it to spirt its saliva, which we collected on a little sugar of milk, and at once prepared, by trituration.

Prover: _Bruno Vidal._

_First day._—1. Extreme heaviness of the head, at 2. Aversion to work, with inability, the whole afternoon.

_Second day._—Pain at the sacrum, worse when rising, stooping or sitting. Almost continual expansive pressure in the orbits, and sensation of internal itching; he is obliged to rub his eyes with the palm of his hand. 5. Itching at the pubis. Itching at the face. Violent itching at the lips.

_Third day._—Pain at the inner part of the right knee. Easy stool. 10. Itching, almost all over. Not disposed to study. Less active than usual. Expansive pressure and itching in the orbits. The pain at the sacrum continues.

_Fourth day._—15. The pain at the sacrum is less; the pain at the knee has ceased. Expansive pressure and itching in the orbits. Itching almost all over. Constant erections without desire; not disposed to intellectual labor, not very active.

_Fifth to tenth day._—Laziness of mind as before. 20. Constant erections, but no desire. Itching and expansive sensation in the orbits.

_Eleventh day._—No sleep.

_Twelfth day._—Prickling at the right big toe.

_Thirteenth day._—Crampy pain at the outer side of the right leg. 25. Red pimple, which breaks and leaves a black spot in its place. Pricking in the pit of the stomach. Pinching at the inside of the left elbow.

_Fourteenth to fifteenth day._—Pressure at the cartilages of the false ribs. Loathing of study.

_Seventeenth to eighteenth day._—30. The eyes are red and smart. A former fungus bleeds. The orbits feel larger, and as if they were in contact with the orbital walls. Aversion to work. He is apt to forget things which he had been occupied with a moment ago.

_Nineteenth day._—35. The eyes smart and are painful when touched.

_Twentieth to Thirty-fifth day._—Careless. Lazy and discouraged. No disposition to work. Weak memory. 40. The upper portion of the orbits seems to be in contact with the orbital walls, especially at night. He is obliged to rub his face in the morning. Formication of the lower jaw. Itching at the lumbar vertebræ. Itching at the anus. 45. A black spot on the right outer ankle, which had remained after a pimple, continues.

_Thirty-sixth day._—Large red pimple on the occiput.

_Thirty-eighth day._—Very gay in the evening. Disposed to talk about merry things.

_Thirty-ninth day._—Gay. Lively. 50. The pimple at the nape of the neck remains. Itching at the lumbar vertebræ. Pain in front of the lobule of the left ear. Ganglion on the sole of the right foot. Excoriation of the left masseter muscle, discharging a little sanguinolent humor. 55. Heaviness of the head after a walk. The eyes smart and are painful when touched. Sleeps for an hour, in the middle of the day, contrary to habit. Sad, he avoids company. He is unable to act with decision, he forms projects and does not accomplish them. 60. Tingling in the lumbar region. Dreams every night, does not recollect his dreams on waking. Pressure on the right side of the forehead. Taciturn and gloomy. Painful sensation under the false ribs. 65. Itching at the sacrum. (Sense of weakness in the whole left side of the head.) Prickings in the tips of the fingers of the right hand and the left toes. Pimples on the forehead. Weakness of mind and memory, less in the evening. 70. Acute lancinations in the left temple. Acute pain in the right wrist. Continual headache. Pain in the extensor muscles of the right arm. Pimple on the right wrist. 75. Violent itching. Drowsy. Poetical and philosophical dreams. Exalted imagination.

ARRANGEMENT ACCORDING TO HAHNEMANN.

1. Sad, he avoids company. Exalted imagination. Indolence of mind. Merry and talkative. 5. Pressure on the right side of the forehead. Darting in the left temple. Heaviness of the head. Expansive pressure in the orbits, and sensation of internal itching. The eyes are red and smart. 10. The orbits feel larger, and as if in contact with the orbital walls. Formication of the lower jaw. Violent itching at the lips. Itching of the pubis. Erections without desire. 15. Pain under the false ribs. Tingling in the lumbar region. Pain at the sacrum, worse when rising. Itching at the lumbar vertebræ. Prickings in the tips of the right fingers. 20. Acute pain in the right wrist. Pain at the right knee. Prickling at the big toe. Poetical dreams. Red pimple, leaving a black spot after breaking. 25. Excoriation at the left masseter muscle. Aversion to work. Itching all over.

JACARANDA CAROBA. (D.C.)

JAC. BIGNONIA CAROBA. (WELL.)

This is a tree with white wood, the ramose top of which attains a height of from 20 to 28 feet. Leaves pennate, tri- or quadrijugate, composed of from five to nine opposite, sessile, glabrous and oval folioles. Flowers large, violet-colored, on pedicles that are expanded at their extremities, and forming ramose terminal panicles. Calix tubulous, with five teeth, corolla tubulous, slightly pubescent externally, and expanding at its summit into a limb with five obtuse divisions. Stamens five, one of which is rudimentary; ovary avoïd, surmounted by a simple style terminating in a bilamellary stygma. The husks are linear and flat. The caroba is very common in Brazil, in gardens and on plantations; it blossoms in September. We employ the flower.

Several varieties of the caroba are used in Brazil for the treatment of syphilitic diseases. For our provings we have selected the Jacaranda caroba, which has furnished results as complete as could be desired. We consider this drug of great importance in the treatment of chancres.

_First day._—1. Stitch at the heart; the heart seems to beat slowly in placing the hand upon it, at 9 in the evening. Stitch and pulling below the stomach, on the right side, at midnight. Dryness and pricking all over.